Two sample MR report
CDC42EP1_Monocyte (Mono) against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | -0.0109071 | 0.1509764 | 0.9540880 |
| Weighted median | 3 | 0.0191675 | 0.0112080 | 0.0872376 |
| Inverse variance weighted | 3 | 0.0184977 | 0.0091594 | 0.0434311 |
| Simple mode | 3 | 0.0204084 | 0.0127891 | 0.2516034 |
| Weighted mode | 3 | 0.0204580 | 0.0116516 | 0.2212050 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.1019760 | 1 | 0.7494712 |
| Inverse variance weighted | 0.1400491 | 2 | 0.9323709 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0223594 | 0.1145909 | 0.877322 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 2.32e-05 | 0 | TRUE | 0.6480497 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
